Can we buy an artwork directly from an artist's studio?
The collector @raph_is answers your questions and sheds light on the art market.
Of course it is possible but not in all cases! It will be easier with emerging artists who are not yet well followed or represented. It's up to you to find the "early" artists before the galleries.
But contacting an artist to sell direct becomes difficult once the artist is represented by one or more galleries. I know several cases of people who, by dint of insistence, have been blacklisted from their galleries! It's up to you to find the right measure. Also, don't forget that buying in a gallery will also give you other privileges, such as having access to other artists or being advised on future purchases.